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Figure 1 | BMC Proceedings

Figure 1

From: Use of principal components to aggregate rare variants in case-control and family-based association studies in the presence of multiple covariates

Figure 1

Top 30 genes associated with Q1 using the principal components and collapsing method with a case-control design. (a) Association with Q1 adjusting for age, sex, population, and smoking. (b) Association with Q1 adjusting for age, sex, population, smoking, and FLT1. Box plots represent the distribution of the 200 P-values of the 200 replicates for the 30 genes with the highest median P-values.

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