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Figure 2 | BMC Proceedings

Figure 2

From: Use of principal components to aggregate rare variants in case-control and family-based association studies in the presence of multiple covariates

Figure 2

Top 30 genes associated with disease phenotype using the principal components and collapsing method with a case-control design. (a) Association with disease adjusting for age, sex, population, and smoking. (b) Association with disease adjusting for age, sex, population, smoking, and Q1. Box plots represent the distribution of the 200 P-values of the 200 replicates for the 30 genes with the highest median P-values.

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