Table 1 Characteristics of the studied genes
Chromosome | Gene | K | MAF (%) | V | K (V) > 5% | 5% >K (V) > 1% | K (V) < 1% |
|---|---|---|---|---|---|---|---|
Causal genes | |||||||
1 | ARNT | 18 | 0.07; 43.11 | 5 | 1 (0) | 2 (1) | 15 (4) |
1 | ELAVL4 | 10 | 0.07; 43.11 | 2 | 2 (0) | 1 (0) | 7 (2) |
13 | FLT1 | 35 | 0.07; 29.05 | 1 | 3 (1) | 7 (2) | 25 (8) |
5 | FLT4 | 10 | 0.07; 2.08 | 2 | 0 (0) | 2 (0) | 8 (2) |
14 | HIF1A | 8 | 0.07; 1.2 | 4 | 0 (0) | 1 (1) | 7 (3) |
19 | HIF3A | 21 | 0.07; 38.52 | 3 | 4 (0) | 2 (0) | 15 (3) |
4 | KDR | 16 | 0.07; 16.5 | 10 | 1 (1) | 1 (1) | 14 (8) |
6 | VEGFA | 6 | 0.07; 2.37 | 1 | 0 (0) | 1 (0) | 5 (1) |
4 | VEGFC | 1 | 0.07; 0.07 | 1 | 0 (0) | 0 (0) | 1 (1) |
Noncausal genes | |||||||
1 | PTGFR | 16 | 0.07; 1.69 | 0 | 0 | 3 | 13 |
1 | IFI44 | 22 | 0.07; 11.33 | 0 | 1 | 1 | 20 |
1 | FAM73A | 10 | 0.07; 0.5 | 0 | 0 | 0 | 10 |
17 | MAPT | 27 | 0.07; 35.58 | 0 | 5 | 7 | 15 |
1 | CTSS | 6 | 0.07; 33.28 | 0 | 1 | 1 | 4 |
5 | FOXI1 | 15 | 0.07; 37.30 | 0 | 2 | 0 | 12 |
2 | LY75 | 83 | 0.07; 45.91 | 0 | 11 | 12 | 60 |