Figure 2

Pairwise scatterplots between five different strategies. (a) Estimated power of detecting the Q2 risk genes for a pair of methods. Each point represents a Q2 risk gene whose coordinate indicates the power estimates from two different strategies. (b) False-positive rate of Q2 control genes for a pair of methods. Each point represents a Q2 control gene whose coordinate indicates the false-positive rates from a pair of strategies. mdmr_rvt, MDMR using only rare variants; mantel_rvt, Mantel test using only rare variants; collapse_rvt, collapsing analysis using only rare variants; mdmr_allvar, MDMR using all variants; mantel_allvar, Mantel test using all variants.