Identification of functional rare variants in genome-wide association studies using stability selection based on random collapsing

Table 1 Top 10 ranked genes for trait Q1 in replicate 1

Gene	Functional SNPs	MAF	β ^b	Stability^c
FLT1 ^a	C13S431	0.02	0.74	1
	C13S522	0.03	0.62	1
	C13S523	0.07	0.65	1
	C13S320	<0.01	0.2	0.95
	C13S524	<0.01	0.62	0.94
	C13S399	<0.01	0.4	0.92
	C13S567	<0.01	0.17	0.88
	C13S505	<0.01	0.45	0.87
BRWD1	–	–	–	1
KDR ^a	C4S1884	0.02	0.3	0.97
	C4S1889	<0.01	0.94	0.72
	C4S1877	<0.01	1.08	0.67
	C4S1890	<0.01	0.42	0.66
	C4S1873	<0.01	0.58	0.64
	C4S1874	<0.01	0.47	0.63
	C4S1879	<0.01	0.62	0.63
C14ORF159	–	0.18	–	0.79
C1ORF122	–	<0.01	–	0.7
ZNF502	–	0.24	–	0.79
VEGFA ^a	C6S2981	<0.01	1.2	0.62
HNRPUL1	–	<0.01	–	0.58
FMNL3	–	<0.01	–	0.56
AIF1	–	0.05	–	0.49

ISSN: 1753-6561