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Table 4 Comparison of ranking approaches

From: Identification of functional rare variants in genome-wide association studies using stability selection based on random collapsing

Ranka

Single-marker test

Collapsing method

CMC method

SORC method

1

FLT1 b

TBX18

FLT1 b

FLT1 b

2

OR2T34

FLT1 b

TBX18

BRWD1

3

LRRK2

AMPD3

AMPD3

KDR b

4

BRCA1

C8ORF31

C8ORF31

C14ORF159

5

PPP1R14BP1

SLCO1A2

ADAM7

C1ORF122

6

HSZFP36

ADAM7

TMEM67

ZNF502

7

C9ORF66

C9ORF66

SBF2

VEGFA b

8

ABL2

AIF1

KIAA0802

HNRPUL1

9

AIF1

SBF2

AIF1

FMNL3

10

RUNX2

FARP1

FARP1

AIF1

  1. a Genes are ordered by the rank of their SNPs’ −log10(p-value).
  2. b Genes containing at least one true functional variant