Table 3 Ten most frequent genes in significant PharmGKB pathways and GO processes using the weighted approach
From: A weighted accumulation test for associating rare genetic variation with quantitative phenotypes
PharmGKB | Number of nonsynonomous SNPs | GO | Number of nonsynonomous SNPs |
|---|---|---|---|
VEGFA | 2 | FLT1 | 20 |
FLT1 | 20 | KDR | 11 |
SRC | 1 | VEGFA | 2 |
HSP90AA1 | 9 | KIT | 5 |
KDR | 11 | ARNT | 9 |
PRKCA | 2 | PTK2B | 4 |
HIF1A | 6 | HIF1A | 6 |
PTK2 | 5 | SHH | 4 |
SHC1 | 3 | ROR2 | 2 |
ARNT | 9 | NRP1 | 1 |