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Table 4 Ten most frequent genes in significant PharmGKB pathways and GO processes using the unweighted approach

From: A weighted accumulation test for associating rare genetic variation with quantitative phenotypes

PharmGKB

Number of nonsynonomous SNPs

GO

Number of nonsynonomous SNPs

VEGFA

2

FLT1

20

FLT1

20

VEGFA

2

SRC

1

KDR

11

HSP90AA1

9

KIT

5

HIF1A

6

ARNT

9

PRKCA

2

PTK2B

4

KDR

11

PDGFB

3

SHC1

3

SHH

4

PTK2

5

EGFR

4

ARNT

9

ROR2

2

  1. Bold denotes genes that were found using both databases.