Joint association analysis of bivariate quantitative and qualitative traits

BMC Proceedings

Table 2 Type I error rate of the association tests at a significance level of 5%

SNP	MAF	Joint analysis			Univariate analysis
		H₀: γ₁ = 0	H₀: γ₂ = 0	H₀: γ₁ = γ₂ = 0	H₀: γ₁ = 0	H₀: γ₂ = 0	H₀: γ₁ = γ₂ = 0
C13S722	0.0007	0.000	0.030	0.010	0.000	0.030	0.025
C13S202	0.0022	0.005	0.065	0.055	0.005	0.065	0.055
C13S556	0.0022	0.035	0.020	0.025	0.050	0.020	0.025
C13S1580	0.0022	0.035	0.025	0.015	0.040	0.025	0.025
C13S398	0.0122	0.050	0.050	0.050	0.050	0.050	0.060
C13S1004	0.0122	0.050	0.030	0.060	0.050	0.030	0.050

γ₁ is the additive SNP effect on the qualitative trait. γ₂ is the additive SNP effect on the quantitative trait.

ISSN: 1753-6561