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Figure 1 | BMC Proceedings

Figure 1

From: Association tests for rare and common variants based on genotypic and phenotypic measures of similarity between individuals

Figure 1

Quantile-quantile plot of p -values of KBAT and QT-KBAT based on permutations and the expected p -values assuming uniform distribution. Restricting the analysis to nonsynonymous SNPs, we calculate the p-values for the case-control and quantitative trait associations based on 2,000 permutations. The plot for quantitative traits is based on the association test with the trait Q1 for a sample of 1,000 genes, and for the case-control test the plot is for all 2,194 genes with at least one nonsynonymous SNP. For each gene the p-value is calculated using a random selection of one of the 200 replicate data sets.

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BMC Proceedings

ISSN: 1753-6561

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