Introduction
Maternal infection during pregnancy is a risk factor for certain psychiatric illnesses with a neurodevelopmental component, such as schizophrenia and cerebral palsy. Pathology is thought to result from the exposure of the foetal brain to pro-inflammatory cytokines stimulated during the inflammatory response that influence developmental processes via their actions on neurones and glial cells. In experimental animals, behavioural outcomes relevant to such disorders have been observed in the offspring of infected dams - this study therefore sought to determine whether behavioural change was present in our murine model of immune activation.