Figure 4

Precision and recall plots of each stage with respect to different values of the network distance parameter ℓ. Precision and recall plots of each stage, in prediction of CRC stages of samples in GSE14333 in a 10-fold cross validation framework are shown in (a) and (b) respectively, with respect to different values of the network distance parameter ℓ, as well as the PPI-free approach. Setting ℓ = 3 provides the best performance for most of the cancer stages in terms of both precision and recall, also providing a smaller search space compared to ℓ = 4 and the PPI-free approach.