Table 1 Cell growth and viability at 3 days culture in a 2L conventional bioreactor and in a single use bioreactor

Batch

Viable Cells (cells/ml)

Viability (%)

Viable Cells (cells/ml)

Viability (%)

Viable Cells (cells/ml)

Viability (%)

Viable Cells (cells/ml)

Viability (%)

1

2.90 × 106

97

2.70 × 106

99.1

2.46 × 106

99

1.96 × 106

92.1

2

1.20 × 106

96.5

1.95 × 106

90.5

1.80 × 106

98.9

2.36 × 106

98

3

2.10 × 106

98

3.0 × 106

97

1.90 × 106

98.1

3.50 × 106

99.4

Mean valors

2.08 × 10⁶

97.5

2.55 × 10⁶

97

2.05 × 10⁶

99

2.61 × 10⁶

99.4