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Table 1 Design of the experiment

From: Evaluation of the advanced micro-scale bioreactor (ambr™) as a highthroughput tool for cell culture process development

pH set point

Feed rate

Number of replicates in ambr™ run

Number of replicates in 2L bioreactor run

7.0

-30%

2

0

7.0

-20%

2

1

7.0

-10%

2

1

7.0

Control feed rate

6

1

7.0

+10%

2

1

7.0

+20%

2

1

7

+30%

2

0

6.9

Control feed rate

2

1

7.1

Control feed rate

2

1