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Table 4 Proportion of phenotypic variance of log(SBP) (averaged over 500 replicates, ± SD) explained by simultaneous regression on nongenetic covariates and on sets of equal size (500 markers), defined according to functional annotation and MAF

From: Estimating proportions of explained variance: a comparison of whole genome subsets

Functionality region

All frequencies

Allele frequency

  

Common

Rare

Very rare

All regions

0.233 ± 0.054

0.234 ± 0.053

0.252 ± 0.052

0.250 ± 0.063

Genic

0.241 ± 0.053

0.244 ± 0.053

0.253 ± 0.052

0.250 ± 0.063

Flanking

0.227 ± 0.055

0.227 ± 0.054

0.244 ± 0.053

0.246 ± 0.060