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Table 1 Scenarios of the 12 tests performed in comparing family-based SKAT and burden test using different types of variants (i.e., common vs. rare) and different types of outcome (i.e., DBP vs. SBP)

From: Comparing the power of family-based association tests for sequence data with applications in the GAW18 simulated data

 

Outcome

Approach

Variants included

 

DBP

SBP

Family SKAT

Family burden

Rare variants

Common variants

Test 1

√

 

√

 

√

 

Test 2

√

 

√

  

√

Test 3

√

 

√

 

√

√

Test 4

√

  

√

√

 

Test 5

√

  

√

 

√

Test 6

√

  

√

√

√

Test 7

 

√

√

 

√

 

Test 8

 

√

√

  

√

Test 9

 

√

√

 

√

√

Test 10

 

√

 

√

√

 

Test 11

 

√

 

√

 

√

Test 12

 

√

 

√

√

√

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BMC Proceedings

ISSN: 1753-6561

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