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Table 1 Ranks of 2 causal genes (MAP4 and FLNB) for trait Q1 and mean SBP based on FBAT p values and combined linkage and association p values for simulations 1 to 10.

From: Combined linkage and family-based association analysis improves candidate gene detection in Genetic Analysis Workshop 18 simulation data

   S1 S2 S3 S4 S5 S6 S7 S8 S9 S10
MAP4 Q1 346 3490 1645 3123 1296 2870 976 4890 3103 733
  combined Q1 920 1073 2429 4310 1651 4105 1353 5142 3958 1816
  mean SBP 10 201 479 55 86 9 18 154 3 35
  combined
mean SBP
7 12 12 3 5 3 4 6 2 3
FLNB Q1 3545 2914 4074 2836 5322 3273 4499 1334 3276 4586
  combined Q1 4193 3326 4568 4090 4132 4355 4717 1939 3958 4690
  mean SBP 681 5660 335 317 905 668 590 2372 104 5674
  combined
mean SBP
266 1084 144 9 28 10 240 343 10 517
  1. Useful rank improvements are in bold fonts.