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Table 1 Ranks of 2 causal genes (MAP4 and FLNB) for trait Q1 and mean SBP based on FBAT p values and combined linkage and association p values for simulations 1 to 10.

From: Combined linkage and family-based association analysis improves candidate gene detection in Genetic Analysis Workshop 18 simulation data

  

S1

S2

S3

S4

S5

S6

S7

S8

S9

S10

MAP4

Q1

346

3490

1645

3123

1296

2870

976

4890

3103

733

 

combined Q1

920

1073

2429

4310

1651

4105

1353

5142

3958

1816

 

mean SBP

10

201

479

55

86

9

18

154

3

35

 

combined

mean SBP

7

12

12

3

5

3

4

6

2

3

FLNB

Q1

3545

2914

4074

2836

5322

3273

4499

1334

3276

4586

 

combined Q1

4193

3326

4568

4090

4132

4355

4717

1939

3958

4690

 

mean SBP

681

5660

335

317

905

668

590

2372

104

5674

 

combined

mean SBP

266

1084

144

9

28

10

240

343

10

517

  1. Useful rank improvements are in bold fonts.