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Table 1 Combinations of 9 imprinting settings and 9 no-imprinting settings

From: Detection of imprinting effects for hypertension based on general pedigrees utilizing all affected and unaffected individuals

 

Haplotype frequencya

 

Imprinting modelb

 

No-imprinting modelb

 

DM1

dM1

DM2

dM2

 

φ d / d

φ d / D

φ D / d

φ D / D

 

φ d / d

φ d / D

φ D / d

H1

0.2

0.0

0.1

0.7

I1

0.26

0.28

0.37

0.39

N1

0.26

0.33

0.39

H2

0.3

0.1

0.0

0.6

I2

0.24

0.26

0.42

0.44

N2

0.24

0.34

0.44

H3

0.3

0.0

0.0

0.7

I3

0.18

0.23

0.53

0.58

N3

0.18

0.38

0.58

  1. aHaplotype frequencies are between disease susceptibility locus(with disease allele D and normal allele d) and marker locus (alleles M1 and M2).
  2. bImprinting models are defined in terms of penetrance probabilities: (Ï• d/d , Ï• d/D , Ï• D/d , Ï• D/D ). For the no-imprinting models,Ï• D/d = Ï• d/D .