| Haplotype frequencya |  | Imprinting modelb |  | No-imprinting modelb |
---|
 | DM1 | dM1 | DM2 | dM2 |  |
|
|
|
| Â |
|
|
|
---|
H1 | 0.2 | 0.0 | 0.1 | 0.7 | I1 | 0.26 | 0.28 | 0.37 | 0.39 | N1 | 0.26 | 0.33 | 0.39 |
H2 | 0.3 | 0.1 | 0.0 | 0.6 | I2 | 0.24 | 0.26 | 0.42 | 0.44 | N2 | 0.24 | 0.34 | 0.44 |
H3 | 0.3 | 0.0 | 0.0 | 0.7 | I3 | 0.18 | 0.23 | 0.53 | 0.58 | N3 | 0.18 | 0.38 | 0.58 |
- aHaplotype frequencies are between disease susceptibility locus(with disease allele D and normal allele d) and marker locus (alleles M1 and M2).
- bImprinting models are defined in terms of penetrance probabilities: (Ï•
d/d
, Ï•
d/D
, Ï•
D/d
, Ï•
D/D
). For the no-imprinting models,Ï•
D/d
= Ï•
d/D
.