Use of admixture and association for detection of quantitative trait loci in the Type 2 Diabetes Genetic Exploration by Next-Generation Sequencing in Ethnic Samples (T2D-GENES) study

Table 1 LAMP-LD ancestry estimates for different marker sets and parameters

Marker set	Window size (no. of SNPs)	Average global ancestral proportions			Number of ancestry switches
		European	Native American	African	Mean	Standard deviation
SNP40098	50	0.489	0.455	0.057	26.71	6.47
*SNP40098*	70	*0.491*	*0.453*	*0.056*	*25.51*	*6.06*
SNP40098	100	0.491	0.453	0.056	24.76	5.86
SNP6884	5	0.486	0.459	0.055	14.61	3.63
SNP6884	10	0.494	0.454	0.052	16.55	4.10
SNP637	2	0.430	0.458	0.112	5.02	1.84
SNP637	10	0.497	0.447	0.057	8.82	2.50

All estimates are based on 959 individuals using chromosome 3 markers. Bold italic type denotes ancestry estimates that were used in the subsequent linear regression models.
SNP, single-nucleotide polymorphism.

ISSN: 1753-6561