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Table 1 The number of SNPs reaching three levels of significance (via permutation)

From: Discovering pure gene-environment interactions in blood pressure genome-wide association studies data: a two-step approach incorporating new statistics

Significance level reached

 

<10−3

<10−4

<10−5

G × age*

SBP

150

(0.24%)*

29

(0.46%)

1

(0.0016%)

 

DBP

92

(0.15%)

11

(0.17%)

4

(0.0064%)

G†

SBP

41

(0.65%)

5

(0.0079%)

1

(0.0016%)

 

DBP

58

(0.92%)

6

(0.0095%)

0

(0)

  1. The percentages of the number of significant SNPs out of total number of SNPs (62,915) are shown in parentheses.
  2. *The pure G × age interactions found by 2-step method.
  3. †The main effect of G by I-score.
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BMC Proceedings

ISSN: 1753-6561

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