Practical investigation of the performance of robust logistic regression to predict the genetic risk of hypertension

Table 3 Area under the receiver operating characteristic curve (AUC)

Excluded individuals	Standard logistic regression				Robust logistic regression
	AUC-Age (% Change)		AUC-Age + SNP (% Change)		AUC-Age (% Change)		AUC-Age + SNP (% Change)
None	0.811	(ref.)	0.852	(ref.)	0.811	(ref.)	0.843	(ref.)
62	0.820	+1.1%	0.861	+1.1%	0.820	+1.1%	0.852	+1.0%
58	0.820	+1.1%	0.861	+1.1%	0.820	+1.1%	0.853	+1.2%
60	0.825	+1.7%	0.859	+0.9%	0.825	+1.7%	0.851	+0.9%
24	0.819	+1.0%	0.859	+0.9%	0.819	+1.0%	0.844	+0.0%

AUCs were calculated for the complete set of individuals and after exclusion of the 4 most remarkable outliers. The relative contributions of the variables age and SNP (rs3934103 and rs11918360, respectively) are also shown.

ISSN: 1753-6561