Figure 1

Type I error and power for detecting DBP-related. single-nucleotide variants (SNVs) on chromosome 3. Considering all 169 diastolic blood pressure (DBP)-related SNVs on chromosome 3, the type I error rates were estimated by the false positive rates when Q1 was the null response (a) and when the genotypes are permuted (b); the power was estimated by the true positive rate when DBP was the response (c). A model with or without containing covariates (age, blood pressure medicine status, and sex) is denoted by its name with or without "covar".