Skip to main content

Table 2 p-Values for the top three transcripts based on the analysis of averaged systolic blood pressure (diastolic blood pressure

From: Association analysis of whole genome sequencing data accounting for longitudinal and family designs

    

SBP p-values

Accession ID

Gene

Chr

SMAF

Baseline

Averaged

Repeated-1

Repeated-2

NM_001134364.1

MAP4

3

0.080

<2.2 × 10-16

<2.2 × 10-16

<2.2 × 10-16

<2.2 × 10-16

NM_002375.4

MAP4

3

0.074

<2.2 × 10-16

<2.2 × 10-16

<2.2 × 10-16

<2.2 × 10-16

NM_030885.3

MAP4

3

0.036

<2.2 × 10-16

<2.2 × 10-16

1.6 × 10-15

<2.2 × 10-16

    

DBP p -values

   

Accession ID

Gene

Chr

SMAF

Baseline

Averaged

Repeated-1

Repeated-2

NM_001134364.1

MAP4

3

0.080

<2.2 × 10-16

<2.2 × 10-16

<2.2 × 10-16

<2.2 × 10-16

NM_002375.4

MAP4

3

0.074

4.4 × 10-16

<2.2 × 10-16

<2.2 × 10-16

<2.2 × 10-16

NM_030885.3

MAP4

3

0.036

6.0 × 10-15

2.2 × 10-16

5.3 × 10-15

<2.2 × 10-16

  1. Note: SMAF is the sum of minor allele frequencies (MAFs) of single-nucleotide polymorphisms included in the burden score of the gene.
  2. DBP, diastolic blood pressure; SBP, systolic blood pressure.