The Coordination of biological rhythms with medical treatment is termed Chronotherapy. This therapy utilizes the use of circadian or other rhythmic cycles of the human body in the optimization of treatment. This study examines blood pressure control and serum biochemistry level in early vs. late hemodialysis patients; attempting to identify a significant chronological variance. The parameters explored were chosen due to their tremendous effects on morbidity and mortality of hemodialysis patients. As these patients are amongst the highest risk groups in developing cardiac events; enhancing blood pressure(BP)control is a major contributor to their survival and well-being.