Table 1 Examples for the event types from BioNLP'13 GE task.
From: Bio-event definition in text mining towards event interconnection
| Â | Reactants | Modifiers | Products | Example |
|---|---|---|---|---|
Gene exp | IL-10 | Â | IL-10 | IL-10 production |
Transcription | MBP mRNA | Â | Â | MBP mRNA transcription |
Protein cata | p100 | Â | Â | degradation of the p100 NF-kB protein |
Binding | HOIP, CD40 | Â | HOIP CD40 (inferred) | the association of HOIP with CD40 |
Localization | ΔFKH |  |  | localization of ΔFKH |
Protein modi | p65 | Â | Â | Post-translational modification of NF-kB p65 |
Phosphorylat | NF-kB | Â | NF-kB pho (inferred) | NF-kB p65 phosphorylation |
Ubiquitinati | I-kBα |  | I-kBα ubi (inferred) | ubiquitination, and subsequent degradation of I-kBα |
Acetylation | p65 | Â | p65 ace (inferred) | Acetylation of p65 |
Deacetylation | p65 | histone deacetylase-3 | p65 dea (inferred) | Deacetylation of p65 by histone deacetylase-3 |
Regulation | Ser536 TRAF2 | HOIP | Â | Example 1: point mutation at Ser536 Example 2: HOIP functions downstream of TRAF2 |
Positive reg | PKCα | M-CSF |  | M-CSF stimulated PKCα |
Negative reg | MEK1, MEK2 | Â | Â | inhibits MEK1 and MEK2 |