Table 1 Effect of small molecules used to modulate Akt activity at different time points after infection with H1N1 PR/8
From: Cellular signaling pathways modulated by influenza infection in HEK293 cells
Control | Akt activator (T.O.I) | Akt activator (17hpi) | Akt inhibitor (T.O.I.) | Akt inhibitor (17hpi) | |
|---|---|---|---|---|---|
HA concentration (μg/ml) | 18.4 ± 0.8 | 2.9 ± 0.6 | 35.1 ± 5.2 | 31.2 ± 3.9 | 21.0 ± 4.4 |
TCID50 (IVP/ml) | 1.1E10 | 8.6E09 | 3.6E11 | 5.4E11 | 9.8E09 |