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Table 1 Type I error of FBAT-v with different weighting schemes and using trait Q1

From: Testing rare variants for hypertension using family-based tests with different weighting schemes

Significance level (95 % CI)

Tests

FBAT-v-e

FBAT-v-e-grv

FBAT-v-e-lor

FBAT-v-e-ow

FBAT-v-e-fp

0.01 (−0.004, 0.024)

0.005

0.01

0.0

0.015

0.015

0.05 (0.02, 0.08)

0.065

0.060

0.05

0.065

0.055

0.1 (0.058, 0.142)

0.11

0.1

0.085

0.12

0.095

  1. CI confidence interval, FBAT-v-e FBAT-v with weighted sum weights as in De et al. [11] using empirical variance, FBAT-v-e-fp FBAT-v with functional prediction (fp) weights using empirical variance, FBAT-v-e-grv FBAT-v with genotype risk value (grv) weights using empirical variance, FBAT-v-e-lor FBAT-v with log odds ratio (lor) weights using empirical variance, FBAT-v-e-ow FBAT-v with optimal weight (ow) weights using empirical variance
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BMC Proceedings

ISSN: 1753-6561

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