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Fig. 1 | BMC Proceedings

Fig. 1

From: A multistep approach to single nucleotide polymorphism–set analysis: an evaluation of power and type I error of gene-based tests of association after pathway-based association tests

Fig. 1

Comparison of power for pathway and gene-based tests. a. The power of VC test for each gene is shown, as well as the power of VC test for the corresponding pathway that contains that gene. Blue dots (above the line y = x) represent genes for which the pathway power is higher than the gene power. b. This is the same setup as A, except it shows the power of Burden test for each gene compared to the power of Burden test for its corresponding pathway. In general, pathway tests are more powerful than gene-based tests

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BMC Proceedings

ISSN: 1753-6561

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