Table 1 Summary of the statistically significant results in the GAW20 data
TG–DNA methylation | |||||
|---|---|---|---|---|---|
CpG | Chr: Pos | Gene | Î’ | SE | p Value |
cg06690548 | Chr4: 139162809 | SLC7A11 | −0.97 | 0.07 | 2.99 × 10−4 |
cg07504977 | Chr10: 102131013 | NA | 0.36 | 0.008 | 6.19 × 10−5 |
cg00574958 | Chr11: 68607622 | CPT1A | −1.00 | 0.02 | 1.29 × 10−14 |
cg11024682 | Chr17: 17730095 | SREBF1 | 0.53 | 0.02 | 4.71 × 10−5 |
cg06500161 | Chr21: 43656587 | ABCG1 | 0.54 | 0.02 | 5.61 × 10−4 |
TG–PRS-L | |||||
| Â | Î’ | SE | p Value | ||
PRS-L | 0.05 | 7.68 × 10− 6 | 5.99 × 10−9 | ||
DNA methylation–Predicted TG | |||||
CpG | Chr: Pos | Gene | Î’ | SE | p Value |
cg06690548 | Chr4: 139162809 | SLC7A11 | −0.05 | 2.86 × 10−4 | 2.84 × 10− 3 |
cg00574958 | Chr11: 68607622 | CPT1A | −0.12 | 1.17 × 10− 3 | 3.97 × 10−4 |
DNA methylation–PRS-M | |||||
| Â | CpG | Gene | Î’ | SE | p Value |
PRS-MCPT1A | cg00574958 | CPT1A | 0.006 | 5.80 × 10−6 | 1.08 × 10−2 |
PRS-MABCG1 | cg06500161 | ABCG1 | 0.008 | 3.77 × 10−6 | 2.61 × 10−5 |
TG–Predicted Methylation | |||||
CpG | Chr: Pos | Gene | Î’ | SE | p Value |
cg00574958 | Chr11: 68607622 | CPT1A | −2.36 | 0.37 | 1.28 × 10−4 |