Table 1 Top cis re-mQTLs that were matched to GWAS catalog
SNPs | CpGsite | CpGgene | meQTLp value | CpG and SNP difference (bp) | Disease/trait | Gene in GWAS | SNPfunction |
|---|---|---|---|---|---|---|---|
rs10903129 | cg09222892 | RHCE | 3.20E-36 | −92,575 | Cholesterol, total cholesterol, erythrocyte sedimentation rate | TMEM57 | Intron |
rs2237457 | cg03466198 | GRB10 | 2.82E-16 | −34,294 | Schizophrenia (treatment resistant) | GRB10 | Intron |
rs6120141 | cg14296766 | CBFA2T2 | 7.41E-14 | − 999,855 | Smooth-surface caries | BPIFA2 | Intron |
rs12517906 | cg00514575 | MGAT1 | 4.80E-11 | −127,730 | Weight | OR2Y1-MGAT1 | Upstream |
rs1046896 | cg12045294 | RPTOR | 1.43E-10 | − 239,794 | Glycated hemoglobin levels | FN3KRP | 3′ Untranslated region |
rs11150078 | cg07648639 | MON1B;SYCE1L | 3.21E-10 | − 208,317 | Bipolar disorder (body mass index interaction) | WWOX | Intron |