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Volume 3 Supplement 7

Genetic Analysis Workshop 16


Genetic Analysis Workshop 16. Go to conference site.

St Louis, MO, USA17-20 September 2008

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  1. Content type: Proceedings

    Rheumatoid arthritis (RA) is a complex, chronic inflammatory disease implicated to have several plausible candidate loci; however, these may not account for all the genetic variations underlying RA. Common dis...

    Authors: Odity Mukherjee, Krishna Rao Sanapala, Padmanabhan Anbazhagana and Saurabh Ghosh

    Citation: BMC Proceedings 2009 3(Suppl 7):S82

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  2. Content type: Proceedings

    For Genetic Analysis Workshop 16 Problem 1, we provided data for genome-wide association analysis of rheumatoid arthritis. Single-nucleotide polymorphism (SNP) genotype data were provided for 868 cases and 119...

    Authors: Christopher I Amos, Wei Vivien Chen, Michael F Seldin, Elaine F Remmers, Kimberly E Taylor, Lindsey A Criswell, Annette T Lee, Robert M Plenge, Daniel L Kastner and Peter K Gregersen

    Citation: BMC Proceedings 2009 3(Suppl 7):S2

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  3. Content type: Proceedings

    Genetic Analysis Workshop 16 (GAW16) Problem 2 presented data from the Framingham Heart Study (FHS), an observational, prospective study of risk factors for cardiovascular disease begun in 1948. Data have been...

    Authors: L Adrienne Cupples, Nancy Heard-Costa, Monica Lee and Larry D Atwood

    Citation: BMC Proceedings 2009 3(Suppl 7):S3

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  4. Content type: Proceedings

    The Genetic Analysis Workshop (GAW) 16 Problem 3 comprises simulated phenotypes emulating the lipid domain and its contribution to cardiovascular disease risk. For each replication there were 6,476 subjects in...

    Authors: Aldi T Kraja, Robert Culverhouse, E Warwick Daw, Jun Wu, Andrew Van Brunt, Michael A Province and Ingrid B Borecki

    Citation: BMC Proceedings 2009 3(Suppl 7):S4

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  5. Content type: Proceedings

    Several methods have been proposed to impute genotypes at untyped markers using observed genotypes and genetic data from a reference panel. We used the Genetic Analysis Workshop 16 rheumatoid arthritis case-co...

    Authors: Joanna M Biernacka, Rui Tang, Jia Li, Shannon K McDonnell, Kari G Rabe, Jason P Sinnwell, David N Rider, Mariza de Andrade, Ellen L Goode and Brooke L Fridley

    Citation: BMC Proceedings 2009 3(Suppl 7):S5

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  6. Content type: Proceedings

    Due to the growing need to combine data across multiple studies and to impute untyped markers based on a reference sample, several analytical tools for imputation and analysis of missing genotypes have been de...

    Authors: Brooke L Fridley, Shannon K McDonnell, Kari G Rabe, Rui Tang, Joanna M Biernacka, Jason P Sinnwell, David N Rider and Ellen L Goode

    Citation: BMC Proceedings 2009 3(Suppl 7):S7

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  7. Content type: Proceedings

    To analyze multiple single-nucleotide polymorphisms simultaneously when the number of markers is much larger than the number of studied individuals, as is the situation we have in genome-wide association studi...

    Authors: Soonil Kwon, Jinrui Cui, Shannon L Rhodes, Donald Tsiang, Jerome I Rotter and Xiuqing Guo

    Citation: BMC Proceedings 2009 3(Suppl 7):S9

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  8. Content type: Proceedings

    The results from association studies are usually summarized by a measure of evidence of association (frequentist or Bayesian probability values) that does not directly reflect the impact of the detected signal...

    Authors: Justo Lorenzo Bermejo, Christine Fischer, Anke Schulz, Nadine Cremer, Rebecca Hein, Lars Beckmann, Jenny Chang-Claude and Kari Hemminki

    Citation: BMC Proceedings 2009 3(Suppl 7):S10

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  9. Content type: Proceedings

    The availability of very large number of markers by modern technology makes genome-wide association studies very popular. The usual approach is to test single-nucleotide polymorphisms (SNPs) one at a time for ...

    Authors: George Mathew, Hongyan Xu and Varghese George

    Citation: BMC Proceedings 2009 3(Suppl 7):S11

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  10. Content type: Proceedings

    There is a long-established association between rheumatoid arthritis and HLA-DRβ1. The shared epitope (SE) allele is an indicator of the presence of any of the HLA-DRβ1 alleles associated with RA. Other autoan...

    Authors: Abigail G Matthews, Jia Li, Chunsheng He, Jurg Ott and Mariza de Andrade

    Citation: BMC Proceedings 2009 3(Suppl 7):S12

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  11. Content type: Proceedings

    The North American Rheumatoid Arthritis Consortium case-control study collected case participants across the United States and control participants from New York. More than 500,000 single-nucleotide polymorphi...

    Authors: Sara M Sarasua, Julianne S Collins, Dhelia M Williamson, Glen A Satten and Andrew S Allen

    Citation: BMC Proceedings 2009 3(Suppl 7):S13

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  12. Content type: Proceedings

    We conducted a search for non-chromosome 6 genes that may increase risk for rheumatoid arthritis (RA). Our approach was to retrospectively ascertain three "extreme" subsamples from the North American Rheumatoi...

    Authors: Brian K Suarez, Robert Culverhouse, Carol H Jin and Anthony L Hinrichs

    Citation: BMC Proceedings 2009 3(Suppl 7):S15

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  13. Content type: Proceedings

    Currently, genome-wide association studies (GWAS) are conducted by collecting a massive number of SNPs (i.e., large p) for a relatively small number of individuals (i.e., small n) and associations are made betwee...

    Authors: Min Zhang, Yanzhu Lin, Libo Wang, Vitara Pungpapong, James C Fleet and Dabao Zhang

    Citation: BMC Proceedings 2009 3(Suppl 7):S17

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  14. Content type: Proceedings

    Genetic association of population-based quantitative trait data has traditionally been analyzed using analysis of variance (ANOVA). However, violations of certain statistical assumptions may lead to false-posi...

    Authors: Saurabh Ghosh, Krishna Rao Sanapala, Abhik Ghosh and Sujatro Chakladar

    Citation: BMC Proceedings 2009 3(Suppl 7):S18

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