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Volume 1 Supplement 1

Genetic Analysis Workshop 15: Gene Expression Analysis and Approaches to Detecting Multiple Functional Loci

Proceedings

Genetic Analysis Workshop 15: Gene Expression Analysis and Approaches to Detecting Multiple Functional Loci. Go to conference site.

St. Pete Beach, Florida, USA11-15 November 2006

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  1. Content type: Proceedings

    Authors: Heather J Cordell, Mariza de Andrade, Marie-Claude Babron, Christopher W Bartlett, Joseph Beyene, Heike Bickeböller, Robert Culverhouse, L Adrienne Cupples, E Warwick Daw, Josée Dupuis, Catherine T Falk, Saurabh Ghosh, Katrina A Goddard, Ellen L Goode, Elizabeth R Hauser, Lisa J Martin…

    Citation: BMC Proceedings 2007 1(Suppl 1):S1

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  2. Content type: Proceedings

    For Genetic Analysis Workshop 15 Problem 2, we organized data from several ongoing studies designed to identify genetic and environmental risk factors for rheumatoid arthritis. Data were derived from the North...

    Authors: Christopher I Amos, Wei Vivien Chen, Elaine Remmers, Katherine A Siminovitch, Michael F Seldin, Lindsey A Criswell, Annette T Lee, Sally John, Neil D Shephard, Jane Worthington, Francois Cornelis, Robert M Plenge, Ann B Begovich, Thomas D Dyer, Daniel L Kastner and Peter K Gregersen

    Citation: BMC Proceedings 2007 1(Suppl 1):S3

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  3. Content type: Proceedings

    Data for Problem 3 of the Genetic Analysis Workshop 15 were generated by computer simulation in an attempt to mimic some of the genetic and epidemiological features of rheumatoid arthritis (RA) such as its pop...

    Authors: Michael B Miller, Gregg R Lind, Na Li and Soon-Young Jang

    Citation: BMC Proceedings 2007 1(Suppl 1):S4

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  4. Content type: Proceedings

    Several methods to identify tagging single-nucleotide polymorphisms (SNPs) are in common use for genetic epidemiologic studies; however, there may be loss of information when using only a subset of SNPs. We so...

    Authors: Ellen L Goode, Brooke L Fridley, Zhifu Sun, Elizabeth J Atkinson, Alex S Nord, Shannon K McDonnell, Gail P Jarvik, Mariza de Andrade and Susan L Slager

    Citation: BMC Proceedings 2007 1(Suppl 1):S6

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  5. Content type: Proceedings

    Assuming multiple loci play a role in regulating the expression level of a single phenotype, we propose a new approach to identify cis- and trans-acting loci that regulate gene expression. Using the Problem 1 dat...

    Authors: Pingzhao Hu, Hui Lan, Wei Xu, Joseph Beyene and Celia MT Greenwood

    Citation: BMC Proceedings 2007 1(Suppl 1):S7

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  6. Content type: Proceedings

    Genotype-expression association analysis using linear regression may produce different test results depending on whether founders only or all pedigreed members are used. This difference is not due to the corre...

    Authors: Young Ju Suh, Hye-Soon Lee, Franak Batliwalla and Wentian Li

    Citation: BMC Proceedings 2007 1(Suppl 1):S8

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  7. Content type: Proceedings

    Mutual information (MI) is a robust nonparametric statistical approach for identifying associations between genotypes and gene expression levels. Using the data of Problem 1 provided for the Genetic Analysis W...

    Authors: Silke Szymczak, Angelo Nuzzo, Christian Fuchsberger, Daniel F Schwarz, Andreas Ziegler, Riccardo Bellazzi and Bernd-Wolfgang Igl

    Citation: BMC Proceedings 2007 1(Suppl 1):S9

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  8. Content type: Proceedings

    The mRNA expression levels of genes have been shown to have discriminating power for the classification of breast cancer. Studying the heritability of gene expression levels on breast cancer related transcript...

    Authors: Tian Zheng, Shuang Wang, Lei Cong, Yuejing Ding, Iuliana Ionita-Laza and Shaw-Hwa Lo

    Citation: BMC Proceedings 2007 1(Suppl 1):S10

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  9. Content type: Proceedings

    Rheumatoid arthritis (RA, MIM 180300) is a common and complex inflammatory disorder. The North American Rheumatoid Arthritis Consortium (NARAC) data, as part of the Genetic Analysis Workshop 15 data, consists ...

    Authors: Yuejing Ding, Lei Cong, Iuliana Ionita-Laza, Shaw-Hwa Lo and Tian Zheng

    Citation: BMC Proceedings 2007 1(Suppl 1):S13

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  10. Content type: Proceedings

    In the present paper, we used the North American Rheumatoid Arthritis Consortium data provided for Genetic Analysis Workshop 15 Problem 2 to: 1) estimate the penetrances of PTPN22 and HLA-DRB1 and, 2) test the...

    Authors: France Gagnon, David Hajage, Sabine Plancoulaine and Sophie Tezenas du Montcel

    Citation: BMC Proceedings 2007 1(Suppl 1):S14

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  11. Content type: Proceedings

    We analyzed a case-control data set for chromosome 18q from the Genetic Analysis Workshop 15 to detect susceptibility loci for rheumatoid arthritis (RA). A total number of 460 cases and 460 unaffected controls...

    Authors: Tai-Yue Kuo, Winston Lau, Cheng Hu and Weihua Zhang

    Citation: BMC Proceedings 2007 1(Suppl 1):S15

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  12. Content type: Proceedings

    As genome-wide association studies grow in popularity for the identification of genetic factors for common and rare diseases, analytical methods to comb through large numbers of genetic variants efficiently to...

    Authors: Zhong Li, Tian Zheng, Andrea Califano and Aris Floratos

    Citation: BMC Proceedings 2007 1(Suppl 1):S16

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  13. Content type: Proceedings

    We examined the potential gene × gene interactions and gene × smoking interactions in rheumatoid arthritis (RA) using the candidate gene data sets provided by Genetic Analysis Workshop 15 Problem 2. The multif...

    Authors: Ling Mei, Xiaohui Li, Kai Yang, Jinrui Cui, Belle Fang, Xiuqing Guo and Jerome I Rotter

    Citation: BMC Proceedings 2007 1(Suppl 1):S17

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  14. Content type: Proceedings

    Although single chi-square analysis of the North American Rheumatoid Arthritis Consortium (NARAC) data identifies many single-nucleotide polymorphisms (SNPs) with p-values less than 0.05, none remain significant ...

    Authors: William Tapper, Andrew Collins and Newton E Morton

    Citation: BMC Proceedings 2007 1(Suppl 1):S18

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  15. Content type: Proceedings

    Rheumatoid arthritis (RA) is a disorder with important public health implications. It is possible that there are clinically distinctive subtypes of the disorder with different genetic etiologies. We used the d...

    Authors: Marsha A Wilcox and Andrew T McAfee

    Citation: BMC Proceedings 2007 1(Suppl 1):S20

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