Volume 7 Supplement 2

São Paulo Advanced School of Comparative Oncology: Abstracts

Meeting abstracts

Edited by Cláudia Aparecida Rainho, Patrícia Pintor dos Reis and Silvia Regina Rogatto

Publication of this supplement was funded by the São Paulo Research Foundation (FAPESP).

São Paulo Advanced School of Comparative Oncology.

Águas de São Pedro, Brazil30 September - 6 October 2012

Concatenated PDF 7S2

Page 1 of 3

São Paulo Advanced School of Comparative Oncology (ESPCA)

Authors: Silvia Regina Rogatto

Citation: BMC Proceedings 2013 7(Suppl 2):A1

Content type: Introduction

Published on: 4 April 2013
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The São Paulo Research Foundation, FAPESP

Authors: Carlos Henrique de Brito Cruz

Citation: BMC Proceedings 2013 7(Suppl 2):A2

Content type: Introduction

Published on: 4 April 2013
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Hospital A.C.Camargo

Authors: Fernando Augusto Soares

Citation: BMC Proceedings 2013 7(Suppl 2):A3

Content type: Introduction

Published on: 4 April 2013
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Differentially expressed genes responsible for insensitivity of CD34+ cells to kinase inhibitors in patients with chronic myeloid leukemia

Authors: Caroline FA Moreira-Nunes, Tereza CB Azevedo, Ana CS Beltrão, Larissa TVM Francês, Rodrigo GMA Sousa, Israel T Silva, Artur Silva, Wilson A Silva Jr and José AR Lemos

Citation: BMC Proceedings 2013 7(Suppl 2):O1

Content type: Oral presentation

Published on: 4 April 2013
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Characterizing the role of the alternative NF-κB pathway in diffuse large B-cell lymphoma

Authors: Daisuke Ito and Jaime F Modiano

Citation: BMC Proceedings 2013 7(Suppl 2):O2

Content type: Oral presentation

Published on: 4 April 2013
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A high-resolution system for metabolic imaging of cancer

Authors: Eduardo H Moriyama, Eric Leung, Naz Chaudary, Tuula Kalliomaki, Richard P Hill, Brian C Wilson and Michael Milosevic

Citation: BMC Proceedings 2013 7(Suppl 2):O3

Content type: Oral presentation

Published on: 4 April 2013
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Evaluation of interleukins 8 and 12, CA 15-3 and free circulating DNA as prognostic markers in dogs with mammary tumors

Authors: Gabriela B Gelaleti, Camila Leonel, Marina G Moschetta, Bruna V Jardim, Lívia C Ferreira, Juliana R Lopes, Larissa B Maschio, Naiane N Gonçalves, Thaiz F Borin, Gustavo R Martins and Debora APC Zuccari

Citation: BMC Proceedings 2013 7(Suppl 2):O4

Content type: Oral presentation

Published on: 4 April 2013
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Genomic alteration in hereditary colorectal patients without mutations in mismatch repair genes

Authors: Rolando AR Villacis, Érika MM Santos, Benedito M Rossi, Dirce M Carraro, Luiz P Kowalski and Silvia R Rogatto

Citation: BMC Proceedings 2013 7(Suppl 2):O5

Content type: Oral presentation

Published on: 4 April 2013
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Hematopoietic stem cells have an intrinsic expansion limit

Authors: Shanti Rojas-Sutterlin, André Haman and Trang Hoang

Citation: BMC Proceedings 2013 7(Suppl 2):O6

Content type: Oral presentation

Published on: 4 April 2013
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Acute, but not constitutive, loss of endothelial β3-integrin inhibits tumour growth and angiogenesis

Authors: Veronica Steri, Tim Ellison, Katherine Weilbaecher, Kairbaan Hodivala-Dilke and Stephen D Robinson

Citation: BMC Proceedings 2013 7(Suppl 2):O7

Content type: Oral presentation

Published on: 4 April 2013
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Survival study of 86 bitches with mammary tumors treated at the Veterinary Hospital of the University Anhembi Morumbi, São Paulo, Brazil

Authors: Manoela P Scapinelli and Adriana T Nishiya

Citation: BMC Proceedings 2013 7(Suppl 2):P1

Content type: Poster presentation

Published on: 4 April 2013
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MicroRNAs from peripheral blood mononuclear cells as biomarkers for detection of preclinical fibrosarcoma

Authors: Adriane F Evangelista, Danilo J Xavier, Elza T Sakamoto-Hojo, Eduardo A Donadi, Geraldo A Passos and Marcia MCM Silveira

Citation: BMC Proceedings 2013 7(Suppl 2):P2

Content type: Poster presentation

Published on: 4 April 2013
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Genotype and phenotype of balb/c mouse strain expressing h-2k^b-tsa58- sv40 immortalizing oncogene

Authors: Aline C Custódio, Fabiane CF Brito, Mara S Junqueira, Roger Chammas and José E Belizário

Citation: BMC Proceedings 2013 7(Suppl 2):P3

Content type: Poster presentation

Published on: 4 April 2013
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Ezrin is required for adhesion and migration in invasive breast cancer

Authors: Alvin Szeto, Victoria Hoskin and Bruce E Elliott

Citation: BMC Proceedings 2013 7(Suppl 2):P4

Content type: Poster presentation

Published on: 4 April 2013
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DNA microarray profile of genes regulated by the epigenetic modifier sodium butyrate combined with etoposide in Burkitt’s lymphoma cells

Authors: Ana C Ferreira, Patricia Severino and Claudete E Klumb

Citation: BMC Proceedings 2013 7(Suppl 2):P5

Content type: Poster presentation

Published on: 4 April 2013
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Assesment of normal tissue radiosensitivity in cervical tumors

Authors: Ana TS Carvalho, Hellen S Cintra, Nathany R Barbosa, Juliana CD Pinezi and Renata BA Soares

Citation: BMC Proceedings 2013 7(Suppl 2):P6

Content type: Poster presentation

Published on: 4 April 2013
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Genetic variants involved in specialized DNA replication and their relation with breast cancer risk, disease progression and patient prognosis

Authors: Ana PC Brandalize, Roberto Minozzo, Lavínia Schüller-Faccini, Jean-Sebastien Hoffman, Christophe Cazaux and Patricia Ashton-Prolla

Citation: BMC Proceedings 2013 7(Suppl 2):P7

Content type: Poster presentation

Published on: 4 April 2013
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Tetra-O-methyl nordihydroguaiaretic acid, an inhibitor of Sp1-mediated survivin transcription, induces apoptosis and acts synergistically with chemo-radiotherapy in glioblastoma cells

Authors: Angel M Castro-Gamero, Kleiton S Borges, Daniel A Moreno, Veridiana K Suazo, Mayara M Fujinami, Rosane PG Queiroz, Harley F de Oliveira, Carlos G Carlotti Jr, Carlos A Scrideli and Luiz G Tone

Citation: BMC Proceedings 2013 7(Suppl 2):P8

Content type: Poster presentation

Published on: 4 April 2013
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Differential expression profile of microRNAs associated with human breast cancer progression

Authors: Augusto LF Marino, Adriane F Evangelista, Taciane Macedo, Henrique CS Silveira, Ligia M Kerr, Rene AC Vieira, Adhemar F Longatto and Márcia MCM Silveira

Citation: BMC Proceedings 2013 7(Suppl 2):P9

Content type: Poster presentation

Published on: 4 April 2013
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Regulation of TRAIL expression by PRAME and EZH2 as potential therapeutic target against solid tumors

Authors: Barbara P Mello, Daniel D de Carvalho, Antonio HJFM Campos, Fernando A Soares and Gustavo P Amarante-Mendes

Citation: BMC Proceedings 2013 7(Suppl 2):P10

Content type: Poster presentation

Published on: 4 April 2013
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Evaluation of the anti-angiogenic action of melatonin in breast cancer

Authors: Bruna V Jardim, Lívia C Ferreira, Thaiz F Borin, Marina G Moschetta, Gabriela B Gelaleti, Juliana R Lopes, Larissa B Maschio, Camila Leonel, Naiane N Gonçalves, Gustavo R Martins and Debora APC Zuccari

Citation: BMC Proceedings 2013 7(Suppl 2):P11

Content type: Poster presentation

Published on: 4 April 2013
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Arylamino-nor-β-lapachone derivative-induced apoptosis in human prostate cancer cells: involvement of NAD(P)H:quinone oxidoreductase (NQO1)

Authors: Bruno C Cavalcanti, Hemerson IF Magalhães, Felipe AR Rodrigues, Manoel O Moraes and Cláudia Pessoa

Citation: BMC Proceedings 2013 7(Suppl 2):P12

Content type: Poster presentation

Published on: 4 April 2013
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Evaluation of myeloid metaplasia in canine mixed mammary tumors

Authors: Cecilia B Campos, Patricia A Auler, Angelica C Bertagnolli, Enio Ferreira, Gustavo M Ribeiro, Ana PM Dias, Liliane C Campos and Geovanni D Cassali

Citation: BMC Proceedings 2013 7(Suppl 2):P13

Content type: Poster presentation

Published on: 4 April 2013
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Cancer stem cells in head and neck squamous cell carcinoma

Authors: Christina Karamboulas, Keira Pereira, Elzbieta Hyatt and Laurie E Ailles

Citation: BMC Proceedings 2013 7(Suppl 2):P14

Content type: Poster presentation

Published on: 4 April 2013
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Canine osteosarcoma cells exhibit resistance to aurora kinase inhibitors

Authors: Claire M Cannon, John Pozniak, Milcah C Scott, Daisuke Ito, Brandi H Gorden, Ashley J Graef and Jaime F Modiano

Citation: BMC Proceedings 2013 7(Suppl 2):P15

Content type: Poster presentation

Published on: 4 April 2013
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Molecular characterization of breast tumor cells in sentinel lymph nodes

Authors: Clarissa Torresan, Savana CL Santos, Silma F Pereira, Marcia M Oliveira, Rubens S Lima, Cícero Urban, Raquel Wall, Jordi Camps, Bassem R Haddad, Enilze MSF Ribeiro, Iglenir J Cavalli and Luciane R Cavalli

Citation: BMC Proceedings 2013 7(Suppl 2):P16

Content type: Poster presentation

Published on: 4 April 2013
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The diagnostic importance of invasive micropapillary carcinoma in the canine mammary gland: clinicopathological, immunohistochemical and survival analysis

Authors: Conrado O Gamba, Éverton J Dias, Lorena GR Ribeiro, Liliane C Campos, Alessandra Estrela-Lima, Enio Ferreira and Geovanni D Cassali

Citation: BMC Proceedings 2013 7(Suppl 2):P17

Content type: Poster presentation

Published on: 4 April 2013
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Thalidomide inhibits inflammation and angiogenesis in tumor 4T1 growth in mice

Authors: Cristina M Souza, Cecília B Campos, Ana CA Silva, Míriam P Lopes, Mônica AND Ferreira, Silvia P Andrade and Geovanni D Cassali

Citation: BMC Proceedings 2013 7(Suppl 2):P18

Content type: Poster presentation

Published on: 4 April 2013
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Targeting uroporphyrinogen decarboxylase for head and neck cancer treatment

Authors: Emma Ito, Shijun Yue, Eduardo H Moriyama, Angela B Hui, Inki Kim, Wei Shi, Nehad M Alajez, Nirmal Bhogal, GuoHua Li, Alessandro Datti, Aaron D Schimmer, Brian C Wilson, Peter P Liu, Daniel Durocher, Benjamin G Neel, Brian O’Sullivan…

Citation: BMC Proceedings 2013 7(Suppl 2):P19

Content type: Poster presentation

Published on: 4 April 2013
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Immunohistochemical expression of TGFβ, E-cadherin and vimentin in benign and malignant neoplasias of canine mammary gland

Authors: Erika M Terra, Geórgia M Magalhães, Marcela MP Rodrigues, Renée L Amorim, Noeme S Rocha and Mirela T Costa

Citation: BMC Proceedings 2013 7(Suppl 2):P20

Content type: Poster presentation

Published on: 4 April 2013
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The role of Met, Src and Stat3 in basal-like breast cancer invasion

Authors: E Carefoot, L Raptis, PA Greer and BE Elliott

Citation: BMC Proceedings 2013 7(Suppl 2):P21

Content type: Poster presentation

Published on: 4 April 2013
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Cyr61, a marker of progesterone activity in normal and hyperplasic endometrium of female dogs

Authors: Fabiana A Voorwald, Caio F Tiosso, Carolina F João, Diogo J Cardilli, Renée L Amorim and Gilson H Toniollo

Citation: BMC Proceedings 2013 7(Suppl 2):P22

Content type: Poster presentation

Published on: 4 April 2013
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Analysis of protein profile expressed on the membrane surface of plasma cells, stromal cells and mononuclear cells from bone marrow microenvironment of multiple myeloma patients by mass spectrometry

Authors: Fabricio de Carvalho, Adriana FP Leme, Alisson L Matsuo, Sandra S Matsuda, Bianca A Pauletti, Walter MT Braga, Edgar J Paredes-Gamero, Maria de Lourdes LF Chauffaille and Gisele WB Colleoni

Citation: BMC Proceedings 2013 7(Suppl 2):P23

Content type: Poster presentation

Published on: 4 April 2013
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Genome-wide profiling of copy number alterations in triple-negative breast cancer identifies a region at 19p13 associated with lymph node metastasis

Authors: Felipe Fidalgo, Amanda Gonçalves, Tatiane Rodrigues, Alex Fiorini, Dirce Maria Carraro, Carla Rosenberg and Ana Cristina Victorino Krepischi

Citation: BMC Proceedings 2013 7(Suppl 2):P24

Content type: Poster presentation

Published on: 4 April 2013
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MicroRNAs and cell proliferation in head and neck squamous cell carcinoma

Authors: Flavia M Andreghetto, Maria FG Klingbeil, Renata M Soares, Décio S Pinto-Junior, Mônica B Mathor, Fábio D Nunes and Patricia Severino

Citation: BMC Proceedings 2013 7(Suppl 2):P25

Content type: Poster presentation

Published on: 4 April 2013
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Discovery of molecular determinants of response to targeted therapies in colorectal cancer using patient-derived xenografts (‘xenopatients’)

Authors: Francesco Sassi, Giorgia Migliardi, Eugenia Zanella, Francesco Galimi, Francesca Cottino, Andrea Bertotti and Livio Trusolino

Citation: BMC Proceedings 2013 7(Suppl 2):P26

Content type: Poster presentation

Published on: 4 April 2013
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Analysis of survivin, XIAP and FoxM1 as potential chemoresistance factors in breast cancer cells

Authors: Gabriela N Moraes, Flavia C Vasconcelos, Deborah Delbue, Karina L Silva, Giuliana P Mognol, João P Viola and Raquel C Maia

Citation: BMC Proceedings 2013 7(Suppl 2):P27

Content type: Poster presentation

Published on: 4 April 2013
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Detection of cancer stem cells by immunohistochemistry of canine mammary neoplasias

Authors: Geórgia Modé Magalhães, Erika M Terra, Rosemeri O Vasconcelos, Mayara C Rosolem, Márcio B Bandarra, Pâmela RR Moreira and Antonio C Alessi

Citation: BMC Proceedings 2013 7(Suppl 2):P28

Content type: Poster presentation

Published on: 4 April 2013
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Investigation of ATM, TP53 and MDM2 polymorphisms and their association with outcome of radiotherapy for prostate cancer

Authors: Hellen S Cintra, Juliana CD Pinezi, Ana Terra S Carvalho, Thalles ED Santos, Ricardo D Marciano and Renata BA Soares

Citation: BMC Proceedings 2013 7(Suppl 2):P29

Content type: Poster presentation

Published on: 4 April 2013
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Methylation profile in penile carcinoma reveals unique signature relative to surround tissue and HPV status

Authors: Hellen Kuasne, Ilce MS Cólus, Hector Hernandez-Vargas, Ariane F Busso, Mateus C Barros-Filho, Fábio A Marchi, Cláudia A Rainho, Gustavo C Guimarães, André L Carvalho, Cristovam Scapulatempo Neto, André Lengert, Fernando A Soares, José Vassallo, Zdengo Herceg and Silvia R Rogatto

Citation: BMC Proceedings 2013 7(Suppl 2):P30

Content type: Poster presentation

Published on: 4 April 2013
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Activated Stat5 levels do not increase with cell density in contrast to activated Stat3 levels in breast epithelial cell culture

Authors: Jamaica D Cass, Mulu Geletu, Sandip SenGupta, Bruce E Elliott and Leda Raptis

Citation: BMC Proceedings 2013 7(Suppl 2):P31

Content type: Poster presentation

Published on: 4 April 2013
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Undernutrition in utero increases susceptibility to prostate neoplasias in adult rat after steroid exposure

Authors: Jaqueline C Rinaldi and Sérgio L Felisbino

Citation: BMC Proceedings 2013 7(Suppl 2):P32

Content type: Poster presentation

Published on: 4 April 2013
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p57 kip2 immunohistochemistry: ancillary technique in hydatidiform moles diagnosis

Authors: Jessica Fernández, Rafael Cortés, Aleydah Salazar, Aníbal Pulido, Pablo Dabed and Victoria García

Citation: BMC Proceedings 2013 7(Suppl 2):P33

Content type: Poster presentation

Published on: 4 April 2013
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Hemangiosarcoma and its cancer stem cell sub-population are effectively killed by a toxin targeted through epidermal growth factor and urokinase receptors

Authors: Jill T Schappa, Aric M Frantz, Brandi H Gorden, Erin B Dickerson, Daniel A Vallera and Jaime F Modiano

Citation: BMC Proceedings 2013 7(Suppl 2):P34

Content type: Poster presentation

Published on: 4 April 2013
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Constitutive expression and roles of interleukin-8 in canine hemangiosarcoma

Authors: Jong-Hyuk Kim, Katie L Anderson, Aric M Frantz, Ashley J Graef, Milcah C Scott, Leslie C Sharkey, Timothy D O’Brien, Erin B Dickerson and Jaime F Modiano

Citation: BMC Proceedings 2013 7(Suppl 2):P35

Content type: Poster presentation

Published on: 4 April 2013
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HMGA2 overexpression is associated with differential expression of miRNAs in uterine leiomyomas

Authors: Julia BH Mello, Mateus C Barros-Filho, Priscila Ramos Cirilo, Fábio A Marchi, Anagloria Pontes and Silvia R Rogatto

Citation: BMC Proceedings 2013 7(Suppl 2):P36

Content type: Poster presentation

Published on: 4 April 2013
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Action of melatonin in primary culture of canine mammary tumors

Authors: Juliana R Lopes, Bruna V Jardim, Larissa B Maschio, Marina G Moschetta, Thaiz F Borin, Lívia C Ferreira, Naiane N Gonçalves, Camila Leonel, Gabriela B Gelaleti and Debora APC Zuccari

Citation: BMC Proceedings 2013 7(Suppl 2):P37

Content type: Poster presentation

Published on: 4 April 2013
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TGF-β polymorphism and its expression correlated with CXCR4 expression in human breast cancer

Authors: Julie Massayo Maeda Oda, Karen Brajão de Oliveira, Roberta Losi Guembarovski, Alda Losi Guembarovski, Glauco Akelinghton Freire Vitiello, Patricia Midori Murobushi Ozawa, Bruna Karina Banin Hirata, Vânia Darc de Castro and Maria Angelica Ehara Watanabe

Citation: BMC Proceedings 2013 7(Suppl 2):P38

Content type: Poster presentation

Published on: 4 April 2013
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Canine carcinomas in benign mixed tumours: versican expression and association with invasion

Authors: Karine A Damasceno, Angélica C Bertagnolli, Alessandra Estrela-Lima, Lorena GR Ribeiro, Bruna S Rabelo, Cecília B Campos, André LB Barros and Geovanni D Cassali

Citation: BMC Proceedings 2013 7(Suppl 2):P39

Content type: Poster presentation

Published on: 4 April 2013
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Evaluation of the expression of angiogenic factors in breast cancer after curcumin treatment

Authors: Lívia C Ferreira, Bruna V Jardim, Thaiz F Borin, Marina G Moschetta, Gabriela B Gelaleti, Larissa B Maschio, Camila Leonel, Juliana R Lopes, Naiane N Gonçalves, Gustavo R Martins and Debora APC Zuccari

Citation: BMC Proceedings 2013 7(Suppl 2):P40

Content type: Poster presentation

Published on: 4 April 2013
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