Hindorff LA, Rice KM, Lange LA, Diehr P, Halder I, Walston J, Kwok P, Ziv E, Nievergelt C, Cummings SR, et al: Common variants in the CRP gene in relation to longevity and cause-specific mortality in older adults: the Cardiovascular Health Study. Atherosclerosis. 2008, 197: 922-930. 10.1016/j.atherosclerosis.2007.08.012.
Article
PubMed Central
CAS
PubMed
Google Scholar
Lalonde E, Albrecht S, Ha KC, Jacob K, Bolduc N, Polychronakos C, Dechelotte P, Majewski J, Jabado N: Unexpected allelic heterogeneity and spectrum of mutations in Fowler syndrome revealed by next-generation exome sequencing. Hum Mutat. 2010, 31: 918-923. 10.1002/humu.21293.
Article
CAS
PubMed
Google Scholar
Biesecker LG, Shianna KV, Mullikin JC: Exome sequencing: the expert view. Genome Biol. 2011, 12: 128-10.1186/gb-2011-12-9-128.
Article
PubMed Central
PubMed
Google Scholar
Albert TJ, Molla MN, Muzny DM, Nazareth L, Wheeler D, Song X, Richmond TA, Middle CM, Rodesch MJ, Packard CJ, et al: Direct selection of human genomic loci by microarray hybridization. Nat Methods. 2007, 4: 903-905. 10.1038/nmeth1111.
Article
CAS
PubMed
Google Scholar
Hodges E, Xuan Z, Balija V, Kramer M, Molla MN, Smith SW, Middle CM, Rodesch MJ, Albert TJ, Hannon GJ, et al: Genome-wide in situ exon capture for selective resequencing. Nat Genet. 2007, 39: 1522-1527. 10.1038/ng.2007.42.
Article
CAS
PubMed
Google Scholar
Gnirke A, Melnikov A, Maguire J, Rogov P, LeProust EM, Brockman W, Fennell T, Giannoukos G, Fisher S, Russ C, et al: Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing. Nat Biotechnol. 2009, 27: 182-189. 10.1038/nbt.1523.
Article
PubMed Central
CAS
PubMed
Google Scholar
Wolf PA, D'Agostino RB, Belanger AJ, Kannel WB: Probability of stroke: a risk profile from the Framingham Study. Stroke. 1991, 22: 312-318. 10.1161/01.STR.22.3.312.
Article
CAS
PubMed
Google Scholar
Gress TW, Nieto FJ, Shahar E, Wofford MR, Brancati FL: Hypertension and antihypertensive therapy as risk factors for type 2 diabetes mellitus. Atherosclerosis Risk in Communities Study. N Engl J Med. 2000, 342: 905-912. 10.1056/NEJM200003303421301.
Article
CAS
PubMed
Google Scholar
Levy D, Larson MG, Vasan RS, Kannel WB, Ho KK: The progression from hypertension to congestive heart failure. JAMA. 1996, 275: 1557-1562. 10.1001/jama.1996.03530440037034.
Article
CAS
PubMed
Google Scholar
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D, Maller J, Sklar P, de Bakker PI, Daly MJ, et al: PLINK: A tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet. 2007, 81: 559-575. 10.1086/519795.
Article
PubMed Central
CAS
PubMed
Google Scholar
Wang K, Li M, Hakonarson H: ANNOVAR: Functional annotation of genetic variants from high-throughput sequencing data. Nucleic Acids Res. 2010, 38: e164-10.1093/nar/gkq603.
Article
PubMed Central
PubMed
Google Scholar
Dunn OJ: Multiple comparisons among means. J Am Statist Assoc. 1961, 56: 52-64. 10.1080/01621459.1961.10482090.
Article
Google Scholar
Dudbridge F, Gusnanto A: Estimation of significance thresholds for genomewide association scans. Genet Epidemiol. 2008, 32: 227-234. 10.1002/gepi.20297.
Article
PubMed Central
PubMed
Google Scholar
Hoggart CJ, Whittaker JC, De Iorio M, Balding DJ: Simultaneous analysis of all SNPs in genome-wide and re-sequencing association studies. PLoS Genet. 2008, 4: e1000130-10.1371/journal.pgen.1000130.
Article
PubMed Central
PubMed
Google Scholar
Pe'er I, Yelensky R, Altshuler D, Daly MJ: Estimation of the multiple testing burden for genomewide association studies of nearly all common variants. Genet Epidemiol. 2008, 32: 381-385. 10.1002/gepi.20303.
Article
PubMed
Google Scholar
Benjamini Y, Hochberg Y: Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Statist Soc B (Method). 1995, 57: 289-300.
Google Scholar
Sathirapongsasuti JF, Lee H, Horst BA, Brunner G, Cochran AJ, Binder S, Quackenbush J, Nelson SF: Exome sequencing-based copy-number variation and loss of heterozygosity detection: ExomeCNV. Bioinformatics. 2011, 27: 2648-2654. 10.1093/bioinformatics/btr462.
Article
PubMed Central
CAS
PubMed
Google Scholar
Maher B: ENCODE: The human encyclopaedia. Nature. 2012, 489: 46-48. 10.1038/489046a.
Article
PubMed
Google Scholar