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  1. Genetic markers with rare variants are spread out in the genome, making it necessary and difficult to consider them in genetic association studies. Consequently, wisely combining rare variants into “composite”...

    Authors: Jennifer S Brennan, Yunxiao He, Rose Calixte, Epiphanie Nyirabahizi, Yuan Jiang and Heping Zhang
    Citation: BMC Proceedings 2011 5(Suppl 9):S100
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 5 Supplement 9

  2. How various genetic effects in combination affect susceptibility to certain disease states continues to be a major area of methodological research. Various rare variant models have been proposed, in response t...

    Authors: Lu Cheng, Pingzhao Hu, Jenna Sykes, Melania Pintilie, Geoffrey Liu and Wei Xu
    Citation: BMC Proceedings 2011 5(Suppl 9):S85
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 5 Supplement 9

  3. The advance of high-throughput next-generation sequencing technology makes possible the analysis of rare variants. However, the investigation of rare variants in unrelated-individuals data sets faces the chall...

    Authors: Haitian Wang, Chien-Hsun Huang, Shaw-Hwa Lo, Tian Zheng and Inchi Hu
    Citation: BMC Proceedings 2011 5(Suppl 9):S50
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 5 Supplement 9

  4. We consider the application of Efron’s empirical Bayes classification method to risk prediction in a genome-wide association study using the Genetic Analysis Workshop 17 (GAW17) data. A major advantage of usin...

    Authors: Gengxin Li, John Ferguson, Wei Zheng, Joon Sang Lee, Xianghua Zhang, Lun Li, Jia Kang, Xiting Yan and Hongyu Zhao
    Citation: BMC Proceedings 2011 5(Suppl 9):S46
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 5 Supplement 9

  5. Recent technological advances have allowed us to study individual genomes at a base-pair resolution and have demonstrated that the average exome harbors more than 15,000 genetic variants. However, our ability ...

    Authors: Andrew Jaffe, Genevieve Wojcik, Audrey Chu, Asieh Golozar, Ankit Maroo, Priya Duggal and Alison P Klein
    Citation: BMC Proceedings 2011 5(Suppl 9):S13
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 5 Supplement 9

  13. Authors: Elena A Nechaeva, Tatyana Y Sen’kina, Alexander B Ryzhikov, Irina F Radaeva, Ol’ga G P’yankova, Natal’ya V Danil’chenko, Tatyana M Sviridenko, Marina P Bogryantzeva, Natal’ya V Gilina, Nikolay A Varaksin, Tatyana G Ryabicheva, Irina V Kiseleva and Larisa G Rudenko
    Citation: BMC Proceedings 2011 5(Suppl 8):P104
    Content type: Meeting abstract Published on:

    This article is part of a Supplement: Volume 5 Supplement 8

  14. Authors: Michelle Sabourin, Ying Huang, Prasad Dhulipala, Shannon Beatty, Jian Liu, Peter Slade, Shawn Barrett, Shue-Yuan Wang, Karsten Winkler, Susanne Seitz, Thomas Rose, Volker Sandig, Peggy Lio, Steve Gorfien, Laurie Donahue-Hjelle and Graziella Piras
    Citation: BMC Proceedings 2011 5(Suppl 8):P102
    Content type: Meeting abstract Published on:

    This article is part of a Supplement: Volume 5 Supplement 8

  45. Raw materials are a critical part of any cell culture medium; therefore, it is of utmost importance to understand and characterize them for high-quality product. The raw material characterization (RMC) program...

    Authors: Chandana Sharma, Barry Drew, Kevin Head, Rani Pusuluri and Matthew V Caple
    Citation: BMC Proceedings 2011 5(Suppl 8):P5
    Content type: Meeting abstract Published on:

    This article is part of a Supplement: Volume 5 Supplement 8

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