Schadt EE, Monks SA, Drake TA, Lusis AJ, Che N, Colinayo V, Ruff TG, Milligan SB, Lamb JR, Cavet G, Linsley PS, Mao M, Stoughton RB, Friend SH: Genetics of gene expression surveyed in maize, mouse and man. Nature. 2003, 422: 297-302. 10.1038/nature01434.
Article
PubMed
CAS
Google Scholar
Morley M, Molony CM, Weber TM, Devlin JL, Ewens KG, Spielman RS, Cheung VG: Genetic analysis of genome-wide variation in human gene expression. Nature. 2004, 430: 743-747. 10.1038/nature02797.
Article
PubMed Central
PubMed
CAS
Google Scholar
Cheung VG, Spielman RS, Ewens KG, Weber TM, Morley M, Burdick JT: Mapping determinants of human gene expression by regional and genome-wide association. Nature. 2005, 437: 1365-1369. 10.1038/nature04244.
Article
PubMed Central
PubMed
CAS
Google Scholar
Chesler EJ, Lu L, Shou S, Qu Y, Gu J, Wang J, Hsu HC, Mountz JD, Baldwin NE, Langston MA, Threadgill DW, Manly KF, Williams RW: Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function. Nat Genet. 2005, 37: 233-242. 10.1038/ng1518.
Article
PubMed
CAS
Google Scholar
Hubner N, Wallace CA, Zimdahl H, Petretto E, Schulz H, Maciver F, Mueller M, Hummel O, Monti J, Zidek V, Musilova A, Kren V, Causton H, Game L, Born G, Schmidt S, Muller A, Cook SA, Kurtz TW, Whittaker J, Pravenec M, Aitman TJ: Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease. Nat Genet. 2005, 37: 243-253. 10.1038/ng1522.
Article
PubMed
CAS
Google Scholar
William RBH, Cotsapas CJ, Cowley MJ, Chan E, Nott DJ, Little PFR: Normalization procedures and detection of linkage signal in genetical-genomics experiments. Nat Genet. 2006, 38: 855-856. 10.1038/ng0806-855.
Article
Google Scholar
Anderson TW: An Introduction to Multivariate Statistical Analysis. 1984, New York: John Wiley & Sons, 2
Google Scholar
Ott J, Rabinowitz D: A principal-components approach based on heritability for combining phenotype information. Hum Hered. 1999, 49: 106-111. 10.1159/000022854.
Article
PubMed
CAS
Google Scholar
Almsay L, Blangero J: Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet. 1998, 62: 1198-1211. 10.1086/301844.
Article
Google Scholar
de Andrade M, Atkinson EJ, Fridley BL, Goode EL, McDonnell S, Liu-Mares W, Rabe KG, Sun Z, Slager SL: The genetics of gene expression: comparison of linkage scans using two phenotype normalization methods. BMC Proc. 2007, 1 (Suppl 1): S151-
Article
PubMed Central
PubMed
Google Scholar
Huang Q, Sanja S, Amos C: Ignoring linkage disequilibrium among tightly linked markers induces false-positive evidence of linkage for affected sib pair analysis. Am J Hum Genet. 2004, 75: 1106-1112. 10.1086/426000.
Article
PubMed Central
PubMed
CAS
Google Scholar
Carlson CS, Eberle MA, Rieder MJ, Yi Q, Kruglyak L, Nickerson DA: Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. Am J Hum Genet. 2004, 74: 106-120. 10.1086/381000.
Article
PubMed Central
PubMed
CAS
Google Scholar
Sobel E, Sengul H, Weeks DE: Multipoint estimation of identity-by-descent probabilities at arbitrary positions among marker loci on general pedigrees. Hum Hered. 2001, 52: 121-131. 10.1159/000053366.
Article
PubMed
CAS
Google Scholar
Lehman EL: Nonparametrics: Statistical Methods Based On Ranks. 1975, San Francisco: Holden-Day, Inc, 97-
Google Scholar
Peng B, Yu RK, DeHoff KL, Amos CI: Normalizing a large number of quantitative traits using empirical normal quantile transformation. BMC Proc. 2007, 1 (Suppl 1): S156-
Article
PubMed Central
PubMed
Google Scholar
de Andrade M, Atkinson EJ, Lunde EM, Amos CI, Chen J: Estimating Genetic Components of Variance in Family Studies using the Multic Routines. Technical Report Series No. 78. 2006, Rochester, Minnesota: Department of Health Sciences Research, Mayo Clinic
Google Scholar
de Andrade M, Olswold C, Slusser JP, Tordsen LA, Atkinson EJ, Rabe KG, Slager SL: Identification of genes involved in alcohol consumption and cigarette smoking. BMC Genetics. 2005, 6: S112-10.1186/1471-2156-6-S1-S112.
Article
PubMed Central
PubMed
Google Scholar
de Andrade M, Amos CI: Multivariate linkage analysis. Biostatistical Genetics and Genetic Epidemiology. Edited by: Elson R, Olson J, Palmer L. 2002, New York: John Wiley & Sons, 564-568.
Google Scholar